{"id":7414,"date":"2021-12-16T07:58:32","date_gmt":"2021-12-16T12:58:32","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-for-blodtryckshojning\/"},"modified":"2021-12-16T07:58:32","modified_gmt":"2021-12-16T12:58:32","slug":"angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-for-blodtryckshojning","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/sv\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-for-blodtryckshojning\/","title":{"rendered":"Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 F\u00f6r blodtrycksh\u00f6jning"},"content":{"rendered":"

Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 F\u00f6r blodtrycksh\u00f6jning<\/strong><\/h2>\n

Produktnamn: ANGIOTENSIN II, HUMAN
\nSekvens: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
\nSynonymer: DRVYIHPF;[ILE5]-ANGIOTENSIN 2;HYPERTENSION II HUMAN;L-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE;H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH;FLUORESCIN-NHCS-NH-ASP-ARG- VAL-TYR-ILE-HIS-PRO-PHE-OH;ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH 2CH3CHOOH H2O;ANGIOTENSIN II, HUMAN
\nCAS: 4474-91-3<& >MF: C50H71N13O12
\nMW: 1046,2
\nEINECS: 2017-001-1
\nProduktkategorier: Angiotensin;peptid
\nMol Fil: 4474-91-3.mol<\/p>\n

Det \u00e4r k\u00e4nt att tum\u00f6rv\u00e4vnader inklusive metastaserande lymfk\u00f6rtlar \u00e4r sammansatta av nytillv\u00e4xande k\u00e4rl som saknar autoreglering av blodfl\u00f6det och p\u00e5verkas endast sekund\u00e4rt av de svarande somatiska k\u00e4rlen. Humant angiotensin II (AT II). en vasopressor, introducerades i Japan f\u00f6r att f\u00f6rb\u00e4ttra effektiviteten av systemisk kemoterapi. Hos patienter med olika avancerade cancerformer \u00f6kar iv infusion av AT II f\u00f6r att uppn\u00e5 ett medelblodtryck p\u00e5 1,5 g\u00e5nger baslinjen (men inte \u00f6ver 150 mm Hg) f\u00f6ljt av en bolusinjektion av konventionella cytotoxiska medel blodfl\u00f6det 5-7 g\u00e5nger i tum\u00f6rv\u00e4vnad och \u00f6kar d\u00e4rf\u00f6r l\u00e4kemedelsleveransen till m\u00e5lv\u00e4vnaden vilket resulterar i f\u00f6rb\u00e4ttrade kemoterapeutiska effekter. Denna kemoterapibehandling med inducerad hypertoni kan utf\u00f6ras s\u00e4kert med minimala biverkningar.<\/p>\n

Angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 Kemiska egenskaper<\/strong>
\nKokpunkt 809,08\u00b0C (grov uppskattning)<& >densitet 1,1257 (grov uppskattning)
\nbrytningsindex 1,6700 (uppskattning)
\nRTECS BW2165000
\nlagringstemp. F\u00f6rvara p\u00e5 m\u00f6rk plats, inert atmosf\u00e4r, F\u00f6rvara i frys, under -20\u00b0C
\nform Pulver
\npka pK1: 10,37 (25\u00b0C)
\nf\u00e4rg orange
\nVattenl\u00f6slighet L\u00f6sligt i vatten (25 mg \/ml), och 5 % \u00e4ttiksyra (1 mg\/ml).
\nInChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N
\nCAS DataBase Reference 4474-91-3<\/p>\n

Funktion och till\u00e4mpning av angiotensin II\/ANGIOTENSIN II, HUMAN CAS 4474-91-3<\/strong>
\nAngiotensin II \u00e4r en kort peptid som best\u00e5r av 8 aminosyror, och dess fysiologiska funktion \u00e4r fr\u00e4mst att h\u00f6ja blodtrycket genom att dra ihop sm\u00e5 art\u00e4rer i hela kroppen. Dessutom kan det ocks\u00e5 fr\u00e4mja uts\u00f6ndringen av aldosteron av binjurebarken, som verkar p\u00e5 njurtubuli f\u00f6r att bevara natrium, vatten och kalium, vilket orsakar en \u00f6kning av blodvolymen och blodtrycket.<\/p>\n

Anv\u00e4ndning av angiotensin II\/ ANGIOTENSIN II, HUMAN CAS 4474-91-3<\/strong>
\n1. Hj\u00e4rt- och lungr\u00e4ddning – \u00e4nnu inte godk\u00e4nd ans\u00f6kan
\n2. En peptid involverad i regleringen av blodtrycket
\n3. Angiotensin II \u00e4r ett peptidhormon som b\u00e4st \u00e4r k\u00e4nt som en vasokonstriktor med centrala roller vid kronisk hypertoni, hj\u00e4rtsvikt och stroke. Det \u00e4r en oktapeptid som vanligtvis genereras genom avl\u00e4gsnande av tv\u00e5 rester fr\u00e5n angiotensin I av angiotensin-omvandlande enzym (ACE). Angiotensin II \u00e4r en ligand f\u00f6r minst tv\u00e5 distinkta receptorer, AT1 och AT2, som var och en framkallar distinkta signalv\u00e4gar och fysiologiska svar. Utvecklingen av antagonister f\u00f6r specifika angiotensin II-receptorsubtyper representerar ett v\u00e4rdefullt alternativ till ACE-h\u00e4mmare.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnamn: ANGIOTENSIN II, HUMAN
\nCAS: 4474-91-3
\nMF: C50H71N13O12
\nMW: 1046.2
\nEINECS: 2017-001-1
\nMol Fil: 4474-91-3 .mol<\/p>\n","protected":false},"featured_media":2175,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[422,422,422,422,422,422,422,422,422],"product_tag":[2353,2375],"class_list":{"0":"post-7414","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-blod-och-vaskular-peptid","15":"product_tag-angiotensin-ii-angiotensin-ii-sv","16":"product_tag-human-cas-4474-91-3-for-blood-pressure-raising-sv","17":"desktop-align-left","18":"tablet-align-left","19":"mobile-align-left","21":"first","22":"instock","23":"shipping-taxable","24":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product\/7414","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/comments?post=7414"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/media\/2175"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/media?parent=7414"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_brand?post=7414"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_cat?post=7414"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_tag?post=7414"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}