{"id":8367,"date":"2021-12-16T13:25:55","date_gmt":"2021-12-16T18:25:55","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/puya-levererar-kalcitonin-lax-cas-47931-85-1-for-osteoporos\/"},"modified":"2021-12-16T13:25:55","modified_gmt":"2021-12-16T18:25:55","slug":"puya-levererar-kalcitonin-lax-cas-47931-85-1-for-osteoporos","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/sv\/product\/puya-levererar-kalcitonin-lax-cas-47931-85-1-for-osteoporos\/","title":{"rendered":"Puya levererar kalcitonin lax CAS 47931-85-1 f\u00f6r osteoporos"},"content":{"rendered":"

Puya levererar kalcitonin lax CAS 47931-85-1 f\u00f6r osteoporos<\/strong><\/h2>\n

Produktnamn: Calcitonin lax
\nSynonymer: salmoncalcitonin-(i-32);salmoncalcitonini;tz-ct;Lax Calcitonin Acetate;Salcatonin;CALCITONIN LALMON 250 UG;CalcitoninAcetate;Lax Calcium: H&>Sealmon Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr -Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2\uff0c(Disulfidbrygga: Cys1-Cys7)
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431,85
\n EINECS: 256-342-8
\nProduktkategorier: Aminosyraderivat;Peptid;Calcitonin- och CGRP-receptor
\nMol Fil: 47931-85-1.mol<\/p>\n

Calcitonin Lax \u00e4r ett polypeptidhormon som uts\u00f6ndras av laxens yttersta grenk\u00f6rtel. Det tillh\u00f6r den kalcitoninliknande proteinfamiljen och kan anv\u00e4ndas f\u00f6r att behandla Pagets bensjukdom, postmenopausal osteoporos (br\u00e4ckliga eller sk\u00f6ra ben) eller h\u00f6ga niv\u00e5er av kalcium i blodet (hyperkalcemi). Det verkar ha verkningar v\u00e4sentligen identiska med kalcitoniner av d\u00e4ggdjursursprung, men dess styrka per mg \u00e4r st\u00f6rre och den har en l\u00e4ngre verkningsperiod. Det verkar huvudsakligen genom att h\u00e4mma osteoklastisk benresorption, minska serumkalcium och \u00f6ka renal uts\u00f6ndring av fosfat, kalcium, natriummagnesium och kalium genom att minska tubul\u00e4r reabsorption.<\/p>\n

Naturligt kalcitonin \u00e4r en bioaktiv peptid som uts\u00f6ndras av bisk\u00f6ldk\u00f6rtelcellerna hos d\u00e4ggdjur eller bakg\u00e4larna hos ryggradsdjur, och \u00e4r den huvudsakliga regulatorn av kalciummetabolismen i levande organismer. Laxkalcitoninacetat \u00e4r en syntetisk 32-peptid, och i klinisk forskning har laxkalcitonin anv\u00e4nts i stor utstr\u00e4ckning p\u00e5 kliniken som ett f\u00f6rebyggande och botande l\u00e4kemedel mot osteoporos och andra metabola bensjukdomar.<\/p>\n

Kemiska egenskaper hos Calcitonin lax CAS 47931-85-1<\/strong>
\nCalcitonin lax Kemiska egenskaper
\ndensitet 1,54\u00b10,1 g\/cm3(F\u00f6rutsp\u00e5dd)
\nlagringstemp. \u221220\u00b0C
\nl\u00f6slighet 0,05 M \u00e4ttiksyra: 1 mg\/mL, klart, f\u00e4rgl\u00f6st
\nformigt pulver
\nVattenl\u00f6slighet L\u00f6sligt i vatten vid 1mg\/ml
\nMerck 13,1642
\nInChIKey IYTKRMFJECGBRF -LXQLIYPUSA-N
\nCAS DataBase Reference 47931-85-1(CAS DataBase Reference)<\/p>\n

Funktion och till\u00e4mpning av Calcitonin lax CAS 47931-85-1<\/strong>
\n1. Kalcitoninlax kan anv\u00e4ndas f\u00f6r kalcitoninreceptor\/cAMP-analys f\u00f6r att bed\u00f6ma n\u00e4rvaron av kalcitoninreceptorer uttryckta av TRAP+-celler. Produkten kan ocks\u00e5 anv\u00e4ndas som en testf\u00f6rening f\u00f6r att studera s\u00e5v\u00e4l som f\u00f6r att j\u00e4mf\u00f6ra effekten av kalcitoningenrelaterad peptid (CGRP) och laxkalcitonin (sCT) p\u00e5 magslemhinnan hos r\u00e5ttor utsatta f\u00f6r kyla + fasth\u00e5llningsstress (CRS). [sigma-aldrich]
\n2. Calcitonin, Lax \u00e4r ett kalciumreglerande hormon som uts\u00f6ndras fr\u00e5n parafollikul\u00e4ra celler i sk\u00f6ldk\u00f6rteln hos d\u00e4ggdjur och i icke-d\u00e4ggdjursarter fr\u00e5n den ultimobranchiala k\u00f6rteln. Kalcitoniner \u00e4r enkelkedjiga polypeptider som inneh\u00e5ller 32 aminosyrarester, som visar hypokalcemisk och hypofosfatemisk verkan, med aminosyrastruktur som skiljer sig mellan d\u00e4ggdjursarter. Laxkalcitonin (salkatonin \u00e4r den syntetiska analogen) uppvisar en markant annorlunda sekvens \u00e4n de h\u00f6gre ryggradsdjuren samt mer potent aktivitet. \u00c5lkalcitonin (Elcatonin) har en liknande aminosyra som laxformen men \u00e4r mer stabil \u00e4n naturliga kalcitoniner p\u00e5 grund av fr\u00e5nvaron av disulfidbryggor. [Santa Cruz Biotechnology]
\n3. Den visar hypokalcemisk och hypofosfatemisk verkan, med aminosyrastruktur som skiljer sig mellan d\u00e4ggdjursarter. Laxkalcitonin (salkatonin \u00e4r den syntetiska analogen) uppvisar en markant annorlunda sekvens \u00e4n de h\u00f6gre ryggradsdjuren samt mer potent aktivitet. Det minskar kalcium och fosfat i blodet p\u00e5 grund av h\u00e4mning av resorption av osteoblaster och osteocyter. [alfa-aesar]
\n4. Kalciumreglerande peptidhormon som frig\u00f6rs fr\u00e5n sk\u00f6ldk\u00f6rteln. S\u00e4nker kalciumkoncentrationen i blodet och minskar benresorptionen av osteoklaster. Anv\u00e4nds f\u00f6r terapeutiska till\u00e4mpningar vid osteoporos. Laxkalcitoninpeptidsekvens skiljer sig fr\u00e5n d\u00e4ggdjur men \u00e4r mer potent.[Enzo Life Sciences, Inc.]<\/p>\n

Anv\u00e4ndning av kalcitoninlax CAS 47931-85-1<\/strong>
\nOsteoporos;Hyperkalcemi; Pagets sjukdom ; Reflex sympatisk dystrofi (algodistrofi eller Sudecks sjukdom)<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnamn: Calcitonin lax
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431.85
\nEINECS: 256-342-8
\nMol Fil: 47931-85-1.mol<\/p>\n","protected":false},"featured_media":2112,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[482],"product_tag":[1325],"class_list":{"0":"post-8367","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-osteoporospeptid","7":"product_tag-puya-supply-calcitonin-salmon-cas-47931-85-1-for-osteoporosis-sv","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product\/8367","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/comments?post=8367"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/media\/2112"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/media?parent=8367"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_brand?post=8367"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_cat?post=8367"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_tag?post=8367"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}