{"id":8709,"date":"2021-12-17T03:00:40","date_gmt":"2021-12-17T08:00:40","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/ganirelix-acetate-cas-123246-29-7-gonadotropin-frisattande-hormon-gnrh-antagonister\/"},"modified":"2021-12-17T03:00:40","modified_gmt":"2021-12-17T08:00:40","slug":"ganirelix-acetate-cas-123246-29-7-gonadotropin-frisattande-hormon-gnrh-antagonister","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/sv\/product\/ganirelix-acetate-cas-123246-29-7-gonadotropin-frisattande-hormon-gnrh-antagonister\/","title":{"rendered":"Ganirelix Acetate CAS 123246-29-7 Gonadotropin-fris\u00e4ttande hormon (GnRH) antagonister"},"content":{"rendered":"

Ganirelix Acetate CAS 123246-29-7 Gonadotropin-fris\u00e4ttande hormon (GnRH) antagonister<\/strong><\/h2>\n

Produktnamn: Ganirelix Acetate
\nSynonymer: Ac-DNal-DCpa-DPal-Ser-Tyr-DHar(Et2)-Leu-Har(Et2)-Pro-DAla -NH2;Ganirelixum;ganirelixacetat;GANIRELIX; Ganirelix Acetate USP\/EP\/BP
\nCAS: 123246-29-7
\nMF: C80H113ClN18O13
\nMW: 1570.34
\nEINECS:
\nProduktkategorier: hormoner
\nMol Fil: 123246-29 -7.mol<\/p>\n

Ganirelixacetat \u00e4r en syntetisk dekapeptidf\u00f6rening som liknar endogent gonadotropinfris\u00e4ttande hormon (GnRH) (\u00e4ven k\u00e4nt som luteiniserande hormonfris\u00e4ttande hormon (LHRH)) och \u00e4r en antagonist till GnRH som konkurrerande motverkar gonadotrop GnRH-receptor, och d\u00e4rigenom muterar v\u00e4gen och orsakar snabb och reversibel h\u00e4mning av uts\u00f6ndringen av gonadotropin (luteiniserande hormon LH och follikelstimulerande hormon FSH). Ganirelixacetat h\u00e4mmar LH-uts\u00f6ndring fr\u00e5n hypofysen mer signifikant \u00e4n FSH-uts\u00f6ndring, vilket minskar k\u00f6nshormonproduktionen.<\/p>\n

Funktion och till\u00e4mpning av Ganirelixacetat CAS 123246-29-7<\/strong>
\nGanirelixacetat \u00e4r en analog av GnRH med substitutioner vid resterna 1, 2, 3, 6, 8 och 10. Det \u00e4r inte en superagonist utan snarare en syntetisk dekapeptid med h\u00f6g antagonistaktivitet och den f\u00f6rsta GnRH-antagonisten som marknadsf\u00f6rs. Det \u00e4r godk\u00e4nt f\u00f6r att d\u00e4mpa LH-\u00f6kningar hos kvinnor som genomg\u00e5r fertilitetsbehandling med ovariell hyperstimulering; LH-\u00f6kningar fr\u00e4mjar normalt \u00e4gglossningen. M\u00e5let med detta l\u00e4kemedel \u00e4r att avsev\u00e4rt minska antalet medicineringsdagar som kr\u00e4vs f\u00f6r att undertrycka LH-\u00f6kningen och d\u00e4rigenom bibeh\u00e5lla \u00e4gg i \u00e4ggstockarna. Behandlingscykler f\u00f6r in vitro fertilisering (IVF) initierades historiskt genom administrering av leuprolidacetat f\u00f6r att undertrycka den f\u00f6r tidig fris\u00e4ttning av LH. Detta h\u00e4mmar \u00e4gglossningen s\u00e5 att \u00e4ggen f\u00f6rblir tillg\u00e4ngliga f\u00f6r h\u00e4mtning av en fertilitetsspecialist. F\u00f6r detta \u00e4ndam\u00e5l injiceras leuprolidacetat vanligtvis i s\u00e5 m\u00e5nga som 26 dagar. Kliniska studier har visat att ganirelixacetat kan st\u00e4nga av LH-\u00f6kningen p\u00e5 endast 5 dagars behandling, att d\u00e4mpningen av LH \u00e4r mer uttalad \u00e4n f\u00f6r FSH och att den kortare behandlingstiden minimerar obehagliga biverkningar, s\u00e5som v\u00e4rmevallningar och huvudv\u00e4rk. .<\/p>\n

Det anv\u00e4nds huvudsakligen kliniskt i kontrollerade ovariestimuleringsprotokoll f\u00f6r kvinnor som genomg\u00e5r assisterad reproduktionsteknologi f\u00f6r att f\u00f6rhindra f\u00f6r tidigt luteiniserande hormontoppar och f\u00f6r behandling av fertilitetsst\u00f6rningar orsakade av denna orsak Chemicalbook. L\u00e4kemedlet har f\u00e4rre biverkningar, h\u00f6ga graviditetsfrekvenser och korta behandlingscykler och har betydande kliniska f\u00f6rdelar j\u00e4mf\u00f6rt med liknande l\u00e4kemedel.<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnamn: Ganirelix Acetate
\nCAS: 123246-29-7
\nMF: C80H113ClN18O13
\nMW: 1570.34
\nProduktkategorier: hormoner
\nMol Fil: 123246-29-7.mol<\/p>\n","protected":false},"featured_media":2112,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[445],"product_tag":[1027],"class_list":{"0":"post-8709","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-urogenital-peptid","7":"product_tag-ganirelix-acetate-cas-123246-29-7-gonadotropin-releasing-hormone-gnrh-antagonists-sv","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product\/8709","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/comments?post=8709"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/media\/2112"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/media?parent=8709"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_brand?post=8709"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_cat?post=8709"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_tag?post=8709"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}