{"id":8779,"date":"2021-12-17T03:04:39","date_gmt":"2021-12-17T08:04:39","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/hogkvalitativt-goserelinacetat-cas-145781-92-6-anvands-for-att-behandla-brostcancer\/"},"modified":"2021-12-17T03:04:39","modified_gmt":"2021-12-17T08:04:39","slug":"hogkvalitativt-goserelinacetat-cas-145781-92-6-anvands-for-att-behandla-brostcancer","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/sv\/product\/hogkvalitativt-goserelinacetat-cas-145781-92-6-anvands-for-att-behandla-brostcancer\/","title":{"rendered":"H\u00f6gkvalitativt goserelinacetat CAS 145781-92-6 anv\u00e4nds f\u00f6r att behandla br\u00f6stcancer"},"content":{"rendered":"

H\u00f6gkvalitativt goserelinacetat CAS 145781-92-6 anv\u00e4nds f\u00f6r att behandla br\u00f6stcancer<\/strong><\/h2>\n

Produktnamn: Goserelinacetat
\nSynonymer: PYR-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZAGLY-NH2;[(T-BU)DSER6, (AZA) )GLY10]-LH-RH;[(T-BU)DSER6, (AZA)GLY10]-LUTEINISERANDE HORMONFR\u00c4STANDE HORMON;ICI-118630 acetat;GOSERELIN HCL[PYR-HIS-TRP-SER-TYR-D-SER( T-BU)-LEU-ARG-PRO-AZAGLY-NH2];1-9-luteiniserande hormonfris\u00e4ttande faktor (svin), 6-(o-(1,1-dimetyletyl)-D-serin)-, 2- (aminokarbonyl)hydrazid, acetat (salt); fertilan; GLP-HIS-TRP-SER-TYR-D-SER(TBU)-LEU-ARG-PRO-AZA-GLY-NH2
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nProduktkategorier: Peptid;Pepetider;Aminosyraderivat;Intermedi\u00e4rer & Finkemikalier;Peptider;L\u00e4kemedelsfiler:
\nl\u00e4kemedelsfiler: 145781-92-6.mol<\/p>\n

Goserelinacetat, liksom leuprolidacetat, \u00e4r en syntetisk superagonist nonapeptidanalog av GnRH som har st\u00f6rre styrka \u00e4n det naturliga hormonet. Observera att den inneh\u00e5ller D-Ser(But) och NH-NHCONH2 ist\u00e4llet f\u00f6r Gly6 respektive Gly10-NH2. Det vill s\u00e4ga, den C-terminala modifieringen har helt enkelt en NH som ers\u00e4tter CH2 i Gly, och liksom den C-terminala f\u00f6r\u00e4ndringen i leuprolidacetat h\u00e4mmar detta enzymatisk nedbrytning av peptiden av postprolinkarboxiamidpeptidaset.
\nGoserelinacetat finns tillg\u00e4ngligt i formen av en liten fast pellet som administreras som ett SC-implantat f\u00f6r palliativ behandling av avancerad, metastaserad br\u00f6stcancer hos pre- och perimenopausala kvinnor eller p\u00e5 liknande s\u00e4tt som palliativ vid avancerad prostatacancer. Sk\u00e4let f\u00f6r anv\u00e4ndningen av detta l\u00e4kemedel \u00e4r, som beskrivits ovan, dess f\u00f6rm\u00e5ga som superagonist att bringa niv\u00e5erna av \u00f6stradiol eller testosteron till n\u00e4ra kastratniv\u00e5er, och d\u00e4rmed bromsa utvecklingen av br\u00f6st- respektive prostatakarcinom. Dessutom \u00e4r goserelinacetat godk\u00e4nt f\u00f6r behandling av endometrios i upp till 6 m\u00e5nader.<\/p>\n

Goserelinacetat CAS 145781-92-6 Kemiska egenskaper<\/strong>
\nSm\u00e4ltpunkt >190\u00b0C (dec.)
\nlagring temp. -20\u00b0C
\nl\u00f6slighet H2O: 20 mg\/mL, klar, f\u00e4rgl\u00f6s
\nform vitt pulver
\nInChIKey IKDXDQDKCZPQSZ-JHYYTBFNSA-N
\nCAS DataBase Reference 145781-92-6<\/p>\n

Funktion och till\u00e4mpning Goserelinacetat CAS 145781-92-6<\/strong>
\n1. Anticancer
\n2. injicerbar gonadotropinfris\u00e4ttande hormonsuperagonist (GnRH-agonist) eller luteiniserande hormon antiproliferativ aktivitet vid br\u00f6st-, prostatacancer och endometriecancer
\n3. Syntetisk peptidagonistanalog av LH-RH. Antineoplastisk (hormonell).<\/p>\n","protected":false},"excerpt":{"rendered":"

Produktnamn: Goserelinacetat
\nCAS: 145781-92-6
\nMF: C59H84N18O14
\nMW: 1269.41
\nEINECS: 652-995-1
\nMol Fil: 145781-92-6.mol.<\/p>\n","protected":false},"featured_media":2217,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[384],"product_tag":[965],"class_list":{"0":"post-8779","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-tumor-peptid","7":"product_tag-goserelin-acetate-cas-145781-92-6-used-for-treat-breast-cancer-sv","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product\/8779","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/comments?post=8779"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/media\/2217"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/media?parent=8779"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_brand?post=8779"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_cat?post=8779"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/sv\/wp-json\/wp\/v2\/product_tag?post=8779"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}