{"id":6782,"date":"2021-12-16T06:04:27","date_gmt":"2021-12-16T11:04:27","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/dekapeptid-12-lumixyl-cas-137665-91-9-melanin-olusumunu-inhibe-eder\/"},"modified":"2021-12-16T06:04:27","modified_gmt":"2021-12-16T11:04:27","slug":"dekapeptid-12-lumixyl-cas-137665-91-9-melanin-olusumunu-inhibe-eder","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/tr\/product\/dekapeptid-12-lumixyl-cas-137665-91-9-melanin-olusumunu-inhibe-eder\/","title":{"rendered":"Dekapeptid-12\/ Lumixyl CAS 137665-91-9, melanin olu\u015fumunu inhibe eder"},"content":{"rendered":"<h2><strong>Dekapeptid-12\/ Lumixyl CAS 137665-91-9, melanin olu\u015fumunu inhibe eder<\/strong><\/h2>\n<p>\u00dcr\u00fcn Ad\u0131: Decapeptide-12<br \/>\nE\u015f anlaml\u0131lar: Decapeptide-12;Decapeptide-12\/ Lumixyl;Decapeptide-12 lumixyl \/ kozmetik peptid;L-Tyrosine, L-tyrosyl-L-arginyl-L-seryl-L- arginil-L-lisil-L-tirosil-L-seril-L-seril-L-triptofil-;Dekapeptid-12 USP\/EP\/BP<br \/>\nCAS: 137665-91-9<br \/>\nMF: C65H90N18O17<br \/>\n MW: 1395.52<br \/>\nEINECS:<br \/>\n\u00dcr\u00fcn Kategorileri:<br \/>\nMol Dosya: 137665-91-9.mol<\/p>\n<p>Dekapeptid-12, melanin olu\u015fumunu engelleyen, pigmentasyonu hafifleten, azaltan kozmetik bir hammaddedir. pigmentasyon ve cilt tonunu e\u015fitler ve ayd\u0131nlat\u0131r. Stanford Dermatology&#39;deki ara\u015ft\u0131rmac\u0131lar taraf\u0131ndan geli\u015ftirilmi\u015ftir ve yeni bir peptit aktivitesi olan Tirozinaz&#39;\u0131 (tirozinaz a\u015f\u0131r\u0131 melanin \u00fcretimini te\u015fvik ederek d\u00fczensiz pigmentasyona, koyu lekelere vb. neden olur) etkili bir \u015fekilde inhibe etti\u011fi kan\u0131tlanm\u0131\u015f tek ila\u00e7t\u0131r. Dekapeptid-12, sadece 12 amino asitten olu\u015fan bir oligopeptiddir. Bu oligopeptid, anti-tirozinaz aktivitesi ile bilinir.<\/p>\n<p>Tirozinaz, bitki ve hayvan dokular\u0131nda bulunur ve melanin ve di\u011fer pigmentleri katalize etmekten sorumludur. Dekapeptid-12, cilt koyula\u015fmas\u0131n\u0131 azaltma konusundaki olas\u0131 yetene\u011fi nedeniyle ara\u015ft\u0131r\u0131lmaktad\u0131r. Hayvan modellerinde tirozinaza m\u00fcdahale edebilir ve cildi ayd\u0131nlatabilir. Decapeptid-12, tahri\u015f ve k\u0131zar\u0131kl\u0131k gibi di\u011fer parlat\u0131c\u0131lar\u0131n tipik yan etkileri olmadan hiperpigmentasyon ya\u015fl\u0131l\u0131k lekeleri, g\u00fcne\u015f lekeleri, e\u015fit olmayan cilt tonu ve foto\u011fraf hasar\u0131 g\u00f6r\u00fcn\u00fcm\u00fcn\u00fc azalt\u0131r. Ayr\u0131ca, meyan k\u00f6k\u00fc gibi yat\u0131\u015ft\u0131r\u0131c\u0131 antioksidanlar da hassas cildi rahatlat\u0131r.<\/p>\n<p>Decapeptide-12, tahri\u015f gibi di\u011fer parlat\u0131c\u0131lar\u0131n tipik yan etkileri olmadan, hiperpigmentasyon (ya\u015fl\u0131l\u0131k lekeleri, g\u00fcne\u015f lekeleri, e\u015fit olmayan cilt tonu ve foto\u011fraf hasar\u0131) g\u00f6r\u00fcn\u00fcm\u00fcn\u00fc azalt\u0131r. ve k\u0131zar\u0131kl\u0131k. Ayr\u0131ca, meyan k\u00f6k\u00fc gibi yat\u0131\u015ft\u0131r\u0131c\u0131 antioksidanlar da hassas cildi rahatlat\u0131r.<\/p>\n<p> <strong>Fungsi<\/strong><br \/>\n <strong>Decapeptide-12\/ Lumixyl CAS 137665-91-9&#39;un \u0130\u015flevi ve Uygulamas\u0131<\/strong><br \/>\n Decapeptide-12, bir enzim olan tirozinaza geri d\u00f6n\u00fc\u015f\u00fcml\u00fc olarak ba\u011flan\u0131r. birka\u00e7 farkl\u0131 pigment \u00fcreten h\u00fccrede bulunur. Melanin \u00fcretiminin ilk ad\u0131m\u0131 olan fenollerin oksidasyonunu katalize eden tirozinaz\u0131 \u00f6nler. Memelilerde, tirozinaz sadece melanozomlarda, pigment \u00fcreten h\u00fccreler i\u00e7indeki \u00f6zel b\u00f6lmelerde bulunur.<br \/>\n Tirozinaz t\u00fcrler aras\u0131nda korunmaz ve asl\u0131nda, yak\u0131ndan ili\u015fkili t\u00fcrler aras\u0131nda bile yap\u0131 olarak b\u00fcy\u00fck farkl\u0131l\u0131klar g\u00f6sterebilir. \u0130nsanlarda, tirozinaz\u0131n etkinli\u011findeki farkl\u0131l\u0131klar cilt rengini belirler ve kromozom 11&#39;de bulunan TYR genindeki hafif de\u011fi\u015fikliklerin sonucudur.<br \/>\n Dekapeptid-12, hidrokinon dahil olmak \u00fczere hiperpigmentasyon i\u00e7in \u00f6nceki tedavilerden yakla\u015f\u0131k 17 kat daha g\u00fc\u00e7l\u00fcd\u00fcr. 7 g\u00fcn boyunca k\u00fclt\u00fcrlenmi\u015f melanositlerde yap\u0131lan \u00e7al\u0131\u015fmalar, melanin i\u00e7eri\u011finde %27-43&#39;l\u00fck bir azalma oldu\u011funu g\u00f6stermi\u015ftir.<br \/>\n Dekapeptid-12, birden fazla hayvan denemesinden ge\u00e7mi\u015ftir ve sonunda hiperpigmentasyonu tedavi etmek i\u00e7in ticari \u00fcr\u00fcnlere dahil edilebilir.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00dcr\u00fcn Ad\u0131: Dekapeptid-12\/ Lumixyl<br \/>\nCAS: 137665-91-9<br \/>\nMF: C65H90N18O17<br \/>\nMW: 1395.52<br \/>\nMol Dosya: 137665-91-9.mol<\/p>\n","protected":false},"featured_media":2114,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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