{"id":8198,"date":"2021-12-16T12:23:32","date_gmt":"2021-12-16T17:23:32","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/thymosin-%ce%b11-thymosin-%ce%b11-acetatethymosin-alpha-1-cas-162304-98-7-kronik-hepatit-byi-tedavi-etmek-ve-bagisiklik-sistemini-guclendirmek-icin\/"},"modified":"2021-12-16T12:23:32","modified_gmt":"2021-12-16T17:23:32","slug":"thymosin-%ce%b11-thymosin-%ce%b11-acetatethymosin-alpha-1-cas-162304-98-7-kronik-hepatit-byi-tedavi-etmek-ve-bagisiklik-sistemini-guclendirmek-icin","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/tr\/product\/thymosin-%ce%b11-thymosin-%ce%b11-acetatethymosin-alpha-1-cas-162304-98-7-kronik-hepatit-byi-tedavi-etmek-ve-bagisiklik-sistemini-guclendirmek-icin\/","title":{"rendered":"Thymosin \u03b11\/ Thymosin \u03b11 \/ AcetateThymosin Alpha 1 CAS 162304-98-7 Kronik hepatit B&#39;yi tedavi etmek ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemini g\u00fc\u00e7lendirmek i\u00e7in"},"content":{"rendered":"<h2><strong>Thymosin \u03b11\/ Thymosin \u03b11 \/ AcetateThymosin Alpha 1 CAS 162304-98-7 Kronik hepatit B&#39;yi tedavi etmek ve ba\u011f\u0131\u015f\u0131kl\u0131k sistemini g\u00fc\u00e7lendirmek i\u00e7in<\/strong><\/h2>\n<p>\u00dcr\u00fcn Ad\u0131: Thymosin \u03b11<br \/>\nS\u0131ra: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu -Lys-Glu-Val-Glu-Glu-Ala-Glu-Ala-Glu-Asn-OH<br \/>\nE\u015f anlaml\u0131lar: THYMOSIN ALPHA 1;THYMOSIN ALPHA1 BOVINE;THYMOSIN APHA 1;ZADAXIN;Thymosin \u03b11 Acetate;Thymosin salt;Thymalatefa Asetat tuzu;Timosin \u03b1 1 Asetat(Thymalfasin)<br \/>\nCAS: 62304-98-7<br \/>\nMF: C129H215N33O55<br \/>\nMW: 3108.32<br \/>\nEINECS: 1592732-453-0<br \/>\n\u00dcr\u00fcn Kategorileri: Amino Asit T\u00fcrevler;Peptid;\u00c7e\u015fitli Peptitler<br \/>\nMol Dosya: 62304-98-7.mol<\/p>\n<p>Thymosin-\u03b11 (T-\u03b11), esas olarak ba\u011f\u0131\u015f\u0131kl\u0131k tepkisine y\u00f6nelik \u00e7oklu biyolojik aktiviteleri olan sentetik bir 28-amino asit peptidi Bu ila\u00e7, HBV ve hepatit C vir\u00fcs\u00fc (HCV) enfeksiyonlar\u0131n\u0131n tedavisinde kullan\u0131lmaktad\u0131r ve k\u00fc\u00e7\u00fck h\u00fccreli d\u0131\u015f\u0131 akci\u011fer kanseri (KHDAK), hepatosel\u00fcler karsinom, AIDS ve malign melanom tedavisi i\u00e7in geli\u015ftirilmektedir. T-\u03b11, sitokinlerin etkisini g\u00fc\u00e7lendirebilir ve ayr\u0131ca siklofosfamid, 5-florourasil, dakarbazin gibi sitotoksik ila\u00e7 tedavisinin hematolojik toksisitesini azaltabilir.<\/p>\n<p> <strong>Thymosin \u03b11\/ Thymosin \u03b11 \/ AcetateThymosin Alpha 1 CAS 162304- 98-7 Kimyasal \u00d6zellikler<\/strong><br \/>\nKaynama noktas\u0131 2899.7\u00b165,0 \u00b0C(Tahmini)<br \/>\nyo\u011funluk 1.360\u00b10.06 g\/cm3(Tahmini)<br \/>\ndepolama s\u0131cakl\u0131\u011f\u0131. \u221220\u00b0C<br \/>\n\u00e7\u00f6z\u00fcn\u00fcrl\u00fck Liyofilize Thymosin a1&#39;in steril 18M\u03a9-cm H2O i\u00e7inde 100 \u03bcg\/ml&#39;den az olmayacak \u015fekilde suland\u0131r\u0131lmas\u0131 \u00f6nerilir, bu daha sonra di\u011fer sulu \u00e7\u00f6zeltilere seyreltilebilir.<br \/>\nrenkli Steril Filtrelenmi\u015f Beyaz liyofilize (dondurularak kurutulmu\u015f) toz.<br \/>\nKararl\u0131l\u0131k: Liyofilize Thymosin a1, oda s\u0131cakl\u0131\u011f\u0131nda 3 hafta stabil olmas\u0131na ra\u011fmen, -18\u00b0C&#39;nin alt\u0131nda kurutularak saklanmal\u0131d\u0131r. Suland\u0131r\u0131ld\u0131ktan sonra Thymalfasin 2-7 g\u00fcn aras\u0131nda 4\u00b0C&#39;de saklanmal\u0131 ve ileride kullan\u0131lmak \u00fczere -18\u00b0C&#39;nin alt\u0131nda saklanmal\u0131d\u0131r.<br \/>\nUzun s\u00fcreli saklama i\u00e7in bir ta\u015f\u0131y\u0131c\u0131 protein (%0,1 HSA veya BSA) eklenmesi \u00f6nerilir.&lt;&amp; &gt;L\u00fctfen donma-\u00e7\u00f6z\u00fclme d\u00f6ng\u00fclerini \u00f6nleyin.<\/p>\n<p> <strong>Thymosin \u03b11\/ Thymosin \u03b11 \/ AcetateThymosin Alpha 1 CAS 162304-98-7&#39;nin \u0130\u015flevi ve Uygulamas\u0131<\/strong><br \/>\nThymosin \u03b11, insan timozini ile ayn\u0131 olan kimyasal olarak sentezlenmi\u015f bir timozin \u03b11&#39;dir. a1. Timozin \u03b11 asetillenmi\u015f bir polipeptittir. Thymosin \u03b11 \u015fu anda 35 geli\u015fmekte olan \u00fclkede hepatit B ve C tedavisi i\u00e7in onaylanm\u0131\u015ft\u0131r. Ayr\u0131ca, timozin \u03b11, di\u011fer hastal\u0131klar\u0131n tedavisinde ba\u011f\u0131\u015f\u0131kl\u0131k tepkisini artt\u0131rmak i\u00e7in kullan\u0131l\u0131r.<\/p>\n<p> <strong>Thymosin alpha 1 Faydalar\u0131<\/strong><br \/>\nThymalfasin (thymosin-alpha 1), Thl ba\u011f\u0131\u015f\u0131kl\u0131k tepkisini g\u00fc\u00e7lendirebilen bir ba\u011f\u0131\u015f\u0131kl\u0131k d\u00fczenleyici ajand\u0131r. In vitro: timalfasinin (Ta1) iRGD ile konjugasyonu, fare dalak lenfositlerinin proliferasyonunu art\u0131rarak ilac\u0131n imm\u00fcnomod\u00fclat\u00f6r aktivitesini korur. Ayr\u0131ca, Ta1 tedavisi ile kar\u015f\u0131la\u015ft\u0131r\u0131ld\u0131\u011f\u0131nda, MCF-7 h\u00fccrelerinin Ta1-iRGD tedavisi, apoptoza giren h\u00fccre say\u0131s\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde artt\u0131r\u0131r ve bu da kanser h\u00fccresi b\u00fcy\u00fcmesinin doza ba\u011fl\u0131 bir inhibisyonu ile sonu\u00e7lan\u0131r. <\/p>\n<p>In vivo: Timalfasin&#39;in, ba\u015fta hepatit (a\u011fa\u00e7 ku\u015fu) ve grip (fare) gibi bula\u015f\u0131c\u0131 hastal\u0131klar ve melanom (fare) ve kolorektal gibi kanser olmak \u00fczere ba\u011f\u0131\u015f\u0131kl\u0131k i\u015flev bozuklu\u011funun \u00e7oklu deneysel modellerinde etkinli\u011fe sahip oldu\u011fu g\u00f6sterilmi\u015ftir. Timalfasinin antit\u00fcm\u00f6r etkileri g\u00f6sterdi\u011fi karsinom (s\u0131\u00e7an). <\/p>\n<p> <strong>Thymosin alpha 1 Dozaj<\/strong><br \/>\nBu, v\u00fccut a\u011f\u0131rl\u0131\u011f\u0131n\u0131za ba\u011fl\u0131d\u0131r. \u015eimdiye kadar yap\u0131lan t\u00fcm ara\u015ft\u0131rmalar kemirgen \u00e7al\u0131\u015fmalar\u0131n\u0131 kullanm\u0131\u015ft\u0131r, s\u0131\u00e7anlara ve farelere genellikle KG ba\u015f\u0131na yakla\u015f\u0131k 10 \u03bcg (mcg) oldu\u011fu d\u00fc\u015f\u00fcn\u00fclen etkili bir dozaj enjekte edilir, insanlarda bunun 1,6 \u03bcg e\u015fde\u011feri y\u00fckleme civar\u0131nda oldu\u011fu d\u00fc\u015f\u00fcn\u00fclmektedir. insanlarda KG ba\u015f\u0131na, yani \u015fu durumdaysan\u0131z: <\/p>\n<p>60 KG (132 lb.) o zaman ideal g\u00fcnl\u00fck BPC-157 oral dozunuz 96 \u03bcg (mcg)<br \/>\n70 KG (154 lb.) = &gt; 112 \u03bcg<br \/>\n80 KG (176 lb.) =&gt; 128 \u03bcg<br \/>\n90 KG (198 lb.) =&gt; 144 \u03bcg<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u00dcr\u00fcn Ad\u0131: Thymosin \u03b11<br \/>\nCAS: 62304-98-7<br \/>\nMF: C129H215N33O55<br \/>\nMW: 3108.32<br \/>\nEINECS: 1592732-453-0<br \/>\nMol Dosya: 62304-98-7.mol<\/p>\n","protected":false},"featured_media":2114,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center 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