{"id":8273,"date":"2021-12-16T13:19:31","date_gmt":"2021-12-16T18:19:31","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/yuksek-kaliteli-peptit-somatostatin-asetat-15-28-somatostatin-28-cas-38916-34-6\/"},"modified":"2021-12-16T13:19:31","modified_gmt":"2021-12-16T18:19:31","slug":"yuksek-kaliteli-peptit-somatostatin-asetat-15-28-somatostatin-28-cas-38916-34-6","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/tr\/product\/yuksek-kaliteli-peptit-somatostatin-asetat-15-28-somatostatin-28-cas-38916-34-6\/","title":{"rendered":"Y\u00fcksek Kaliteli Peptit Somatostatin Asetat\/ 15-28-Somatostatin-28 CAS 38916-34-6"},"content":{"rendered":"

Y\u00fcksek Kaliteli Peptit Somatostatin Asetat\/ 15-28-Somatostatin-28 CAS 38916-34-6<\/strong><\/h2>\n

\u00dcr\u00fcn Ad\u0131: Somatostatin Asetat\/ 15-28-Somatostatin-28
\nE\u015f Anlamlar\u0131: Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH ;SoMatotropin Sal\u0131n\u0131m-\u0130nhibit\u00f6r Fakt\u00f6r\u00fc, SRIF, SRIF-14;Siklik somatostatin;SoMatostatin Asetat;B\u00dcY\u00dcME HORMON Sal\u0131m\u0131n\u0131 \u00d6NLEY\u0130C\u0130 FAKT\u00d6R (\u0130NSAN, S\u0131\u011f\u0131r, Domuz, S\u0131\u00e7an, FARE);B\u00dcY\u00dcME HORMON Sal\u0131m\u0131n\u0131 Engelleyen,Zehirleyici,F. MOUSE) 2ACOH 6H2O;H-ALA-GLY-CYS-LYS-ASN-PHE-PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH;H-ALA-GLY-CYS-LYS-ASN-PHE -PHE-TRP-LYS-THR-PHE-THR-SER-CYS-OH (BSA'YA EKLE)
\nCAS: 38916-34-6
\nMF: C76H104N18O19S2
\nMW: 1637.88
\nEINECS: 254-186-5
\n\u00dcr\u00fcn Kategorileri: Amino Asit T\u00fcrevleri;Amino Asitler ve T\u00fcrevleri;Peptid;Amino Asitler 13C, 2H, 15N;Ara \u00fcr\u00fcnler ve \u0130nce Kimyasallar;Pharmaceuticals;peptids pharm
\nMol Dosya: 38916-34-6 .mol<\/p>\n

Somatostatin, ilk kez 1973'te Guillemin taraf\u0131ndan izole edilen ve muhtemelen hipota taraf\u0131ndan \u00fcretilen inhibit\u00f6r fakt\u00f6rlerin en kapsaml\u0131s\u0131 ve en \u00f6nemlisi olan siklik bir 14-peptiddir. lamus. Hipotalamik orijinli somatostatinin temel aktivitesi, \u00f6n hipofizden b\u00fcy\u00fcme hormonu (GH) sal\u0131n\u0131m\u0131n\u0131n inhibisyonudur. Hipofiz t\u00fcm\u00f6rlerinde oldu\u011fu gibi \u00e7ok fazla GH, bir t\u00fcr devlik olan akromegali'ye neden olur. \u00d6te yandan, \u00e7ok az GH c\u00fcceli\u011fe yol a\u00e7ar. Somatostatin ayr\u0131ca pankreasta ve pankreastan hem ins\u00fclin hem de glukagon salg\u0131lanmas\u0131n\u0131 ve ayr\u0131ca \u00e7e\u015fitli ba\u011f\u0131rsak peptitlerinin (\u00f6rne\u011fin, gastrin, sekretin, pepsin ve renin) salg\u0131lanmas\u0131n\u0131 engelledi\u011fi GI yolunda bulunmu\u015ftur. Somatostatinin 3 dakikadan k\u0131sa olan yar\u0131 \u00f6mr\u00fc, terap\u00f6tik bir ajan olarak kullan\u0131lmas\u0131n\u0131 engellemi\u015ftir. Bir\u00e7ok somatostatin t\u00fcrevi, etki s\u00fcresini uzatmak ve\/veya etki se\u00e7icili\u011fini artt\u0131rmak i\u00e7in haz\u0131rlanm\u0131\u015ft\u0131r. Bu yap\u0131-aktivite \u00e7al\u0131\u015fmalar\u0131n\u0131n doruk noktas\u0131, oktreotid asetat\u0131n geli\u015ftirilmesiydi.<\/p>\n

Hipotalamusa ek olarak, serebral korteks, striatum, amigdala, hipokampus ve omurilik, sempatik sinir, gastrointestinal, adac\u0131k, b\u00f6brek, tiroid ve paratiroid bezleri somatostatinde yayg\u0131n olarak da\u011f\u0131lm\u0131\u015ft\u0131r. Beyinde ve gastrointestinal sistemde, GHRIH14'\u00fcn N-terminalinin d\u0131\u015fa do\u011fru bir uzant\u0131s\u0131 olan GHRIH28'in 28 amino asidi safla\u015ft\u0131r\u0131ld\u0131. Somatostatinin in vitro etkisi karma\u015f\u0131kt\u0131r ve sinir sisteminde bir verici veya mod\u00fclasyon i\u015flevi g\u00f6rebilir; somatostatinin gastrointestinal motilite ve sindirim sistemi hormonlar\u0131n\u0131n salg\u0131lanmas\u0131 \u00fczerinde belirli bir inhibit\u00f6r etkisi vard\u0131r; ayn\u0131 zamanda ins\u00fclin ve pankreas Glukagon, renin, paratiroid hormonu ve kalsitonin salg\u0131s\u0131n\u0131 da inhibe eder.<\/p>\n

Somatostatin Acetate\/15-28-Somatostatin-28 CAS 38916-34-6 Kimyasal \u00d6zellikler<\/strong>
\n15-28-Somatostatin-28 Kimyasal \u00d6zellikler
\nKaynama noktas\u0131 1970,9\u00b165,0 \u00b0C(Tahmini)
\nyo\u011funluk 1,43\u00b10,1 g\/cm3(Tahmini)
\ndepolama s\u0131cakl\u0131\u011f\u0131. \u221220\u00b0C
\n\u00e7\u00f6z\u00fcn\u00fcrl\u00fck H2O: 1 mg\/mL
\npka 2,94\u00b10,70(Tahmini)
\ntoz halinde
\nSuda \u00c7\u00f6z\u00fcn\u00fcrl\u00fck Suda \u00e7\u00f6z\u00fcn\u00fcr(25,00\u00b0C 1,00 g\/L) , Metanol.
\nMerck 13,8788
\nBRN 6436064
\nInChIKey NHXLMOGPVYXJNR-ATOGVRKGSA-N<\/p>\n

Somatostatin Asetat\/15-28-Somatostatin-28 CAS<\/strong> <& >
\n1 B\u00fcy\u00fcme hormonu, tiroid uyar\u0131c\u0131 hormon, ins\u00fclin, glukagon salg\u0131lanmas\u0131n\u0131 engelleyebilir.<\/p>\n

2 Test yeme\u011fi ve 5-peptid gastrin taraf\u0131ndan uyar\u0131lan mide asidi salg\u0131s\u0131n\u0131 engelleyebilir ve pepsin ve gastrin sal\u0131n\u0131m\u0131.<\/p>\n

3 Viseral kan ak\u0131\u015f\u0131n\u0131 \u00f6nemli \u00f6l\u00e7\u00fcde azaltabilir, portal bas\u0131nc\u0131n\u0131 azaltabilir, kan ak\u0131\u015f\u0131n\u0131 ve kollateral dola\u015f\u0131m\u0131n bas\u0131nc\u0131n\u0131 azaltabilir, karaci\u011fer kan ak\u0131\u015f\u0131n\u0131 azaltabilir.<\/p>\n

4 Salg\u0131y\u0131 azaltabilir. pankreas\u0131n ve ince ba\u011f\u0131rsak ve safra kesesinin salg\u0131lanmas\u0131n\u0131 sa\u011flar, enzim aktivitesini azalt\u0131r ve pankreas h\u00fccreleri \u00fczerinde koruyucu etkiye sahiptir.<\/p>\n

5 Gastrointestinal sistemin emilimini ve beslenme fonksiyonunu etkileyebilir.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00dcr\u00fcn Ad\u0131: Somatostatin Asetat\/ 15-28-Somatostatin-28
\nCAS: 38916-34-6
\nMF: C76H104N18O19S2
\nMW: 1637.88
\nEINECS: 254-186-5
\nMol Dosyas\u0131 : 38916-34-6.mol<\/p>\n","protected":false},"featured_media":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[],"product_tag":[],"class_list":{"0":"post-8273","1":"product","2":"type-product","3":"status-publish","5":"desktop-align-left","6":"tablet-align-left","7":"mobile-align-left","9":"first","10":"instock","11":"shipping-taxable","12":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product\/8273","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/comments?post=8273"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/media?parent=8273"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_brand?post=8273"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_cat?post=8273"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_tag?post=8273"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}