{"id":8361,"date":"2021-12-16T13:25:52","date_gmt":"2021-12-16T18:25:52","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/osteoporoz-icin-puya-tedarik-kalsitonin-somon-cas-47931-85-1\/"},"modified":"2021-12-16T13:25:52","modified_gmt":"2021-12-16T18:25:52","slug":"osteoporoz-icin-puya-tedarik-kalsitonin-somon-cas-47931-85-1","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/tr\/product\/osteoporoz-icin-puya-tedarik-kalsitonin-somon-cas-47931-85-1\/","title":{"rendered":"Osteoporoz i\u00e7in Puya Tedarik Kalsitonin somon CAS 47931-85-1"},"content":{"rendered":"

Osteoporoz i\u00e7in Puya Tedarik Kalsitonin somon CAS 47931-85-1<\/strong><\/h2>\n

\u00dcr\u00fcn Ad\u0131: Calcitonin salmon
\nE\u015f Anlaml\u0131lar\u0131: salmoncalcitonin-(i-32);salmoncalcitonini;tz-ct;Salmon Calcitonin Acetate;Salcatonin;CALCITONIN SALMON 250 UG;CalcitoninAsetat;Somon Kalsiyum
\nS\u0131ra: H-[ Cys-Ser-Asn-Leu-Ser-Thr-Cys]-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr -Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH2\uff0c(Dis\u00fclfit k\u00f6pr\u00fcs\u00fc: Cys1-Cys7)
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431.85
\n EINECS: 256-342-8
\n\u00dcr\u00fcn Kategorileri: Amino Asit T\u00fcrevleri;Peptid;Kalsitonin ve CGRP resept\u00f6r\u00fc
\nMol Dosya: 47931-85-1.mol<\/p>\n

Kalsitonin Somon, bir polipeptit hormonudur. somonun ultimobranchial bezi. Kalsitonin benzeri protein ailesine aittir ve Paget'in kemik hastal\u0131\u011f\u0131n\u0131, postmenopozal osteoporozu (k\u0131r\u0131lgan veya k\u0131r\u0131lgan kemikler) veya kandaki y\u00fcksek kalsiyum seviyelerini (hiperkalsemi) tedavi etmek i\u00e7in kullan\u0131labilir. Esasen memeli k\u00f6kenli kalsitoninlerle ayn\u0131 etkilere sahip gibi g\u00f6r\u00fcnmektedir, ancak mg ba\u015f\u0131na potensi daha fazlad\u0131r ve etki s\u00fcresi daha uzundur. Esas olarak osteoklastik kemik rezorpsiyonunu inhibe ederek, serum kalsiyumunu azaltarak ve t\u00fcb\u00fcler reabsorbsiyonu azaltarak renal fosfat, kalsiyum, sodyum magnezyum ve potasyum at\u0131l\u0131m\u0131n\u0131 art\u0131rarak \u00e7al\u0131\u015f\u0131r.<\/p>\n

Do\u011fal kalsitonin, memelilerin paratiroid h\u00fccreleri taraf\u0131ndan salg\u0131lanan biyoaktif bir peptittir. veya omurgal\u0131lar\u0131n arka solunga\u00e7lar\u0131d\u0131r ve canl\u0131 organizmalarda kalsiyum metabolizmas\u0131n\u0131n ana d\u00fczenleyicisidir. Somon kalsitonin asetat sentetik bir 32-peptiddir ve klinik ara\u015ft\u0131rmalarda, somon kalsitonin klinikte osteoporoz ve di\u011fer metabolik kemik hastal\u0131klar\u0131 i\u00e7in \u00f6nleyici ve iyile\u015ftirici bir ila\u00e7 olarak yayg\u0131n olarak kullan\u0131lmaktad\u0131r.<\/p>\n

Kalsitonin Somon CAS'\u0131n Kimyasal \u00d6zellikleri 47931-85-1<\/strong>
\nKalsitonin somonu Kimyasal \u00d6zellikler
\nyo\u011funluk 1,54\u00b10,1 g\/cm3(\u00d6ng\u00f6r\u00fclen)
\ndepolama s\u0131cakl\u0131\u011f\u0131. \u221220\u00b0C
\n\u00e7\u00f6z\u00fcn\u00fcrl\u00fck 0,05 M asetik asit: 1 mg\/mL, berrak, renksiz
\ntoz halinde
\nSuda \u00c7\u00f6z\u00fcn\u00fcrl\u00fck Suda 1 mg\/ml'de \u00e7\u00f6z\u00fcn\u00fcr
\nMerck 13,1642
\nInChIKey IYTKRMFJECGBRF -LXQLIYPUSA-N
\nCAS Veri Taban\u0131 Referans\u0131 47931-85-1(CAS Veri Taban\u0131 Referans\u0131)<\/p>\n

Kalsitonin somon CAS 47931-85-1<\/strong>
\n1. Kalsitonin somonu, TRAP+ h\u00fccreleri taraf\u0131ndan eksprese edilen kalsitonin resept\u00f6rlerinin varl\u0131\u011f\u0131n\u0131 de\u011ferlendirmek i\u00e7in kalsitonin resept\u00f6r\u00fc\/cAMP tahlili i\u00e7in kullan\u0131labilir. \u00dcr\u00fcn, kalsitonin geni ile ilgili peptidin (CGRP) ve kalsitonin geni ile ilgili peptidin (CGRP) ve so\u011fuk + k\u0131s\u0131tlama stresine (CRS) maruz kalan s\u0131\u00e7anlarda gastrik mukozal bariyer \u00fczerinde somon kalsitonin (sCT). [sigma-aldrich]
\n2. Kalsitonin, Somon, memeli tiroid parafolik\u00fcler h\u00fccrelerinden ve memeli olmayan t\u00fcrlerde ultimobranchial bezden salg\u0131lanan kalsiyum d\u00fczenleyici bir hormondur. Kalsitoninler, memeli t\u00fcrleri aras\u0131nda farkl\u0131l\u0131k g\u00f6steren, hipokalsemik ve hipofosfatemik etki g\u00f6steren, 32 amino asit kal\u0131nt\u0131s\u0131 i\u00e7eren tek zincirli polipeptitlerdir. Somon kalsitonin (salcatonin sentetik analo\u011fudur), daha y\u00fcksek omurgal\u0131lar\u0131nkinden belirgin \u015fekilde farkl\u0131 bir dizilim ve ayn\u0131 zamanda daha g\u00fc\u00e7l\u00fc aktivite g\u00f6sterir. Y\u0131lan bal\u0131\u011f\u0131 kalsitonin (Elcatonin), somon formuna benzer bir amino aside sahiptir, ancak dis\u00fclfid k\u00f6pr\u00fclerinin olmamas\u0131 nedeniyle do\u011fal kalsitoninlerden daha stabildir. [Santa Cruz Biyoteknoloji]
\n3. Memeli t\u00fcrleri aras\u0131nda farkl\u0131l\u0131k g\u00f6steren amino asit yap\u0131s\u0131 ile hipokalsemik ve hipofosfatemik etki g\u00f6sterir. Somon kalsitonin (salcatonin sentetik analo\u011fudur), daha y\u00fcksek omurgal\u0131lar\u0131nkinden belirgin \u015fekilde farkl\u0131 bir dizilim ve ayn\u0131 zamanda daha g\u00fc\u00e7l\u00fc aktivite g\u00f6sterir. Osteoblastlar ve osteositler taraf\u0131ndan rezorpsiyonun inhibisyonu nedeniyle kan kalsiyum ve fosfat\u0131n\u0131 azalt\u0131r. [alfa-aesar]
\n4. Tiroidden sal\u0131nan kalsiyum d\u00fczenleyici peptit hormonu. Kandaki kalsiyum konsantrasyonunu d\u00fc\u015f\u00fcr\u00fcr ve osteoklastlar taraf\u0131ndan kemik emilimini azalt\u0131r. Osteoporozda terap\u00f6tik uygulamalar i\u00e7in kullan\u0131l\u0131r. Somon kalsitonin peptit dizisi memelilerden farkl\u0131d\u0131r ancak daha g\u00fc\u00e7l\u00fcd\u00fcr.[Enzo Life Sciences, Inc.]<\/p>\n

Calcitonin somon CAS 47931-85-1<\/strong>
\nOsteoporosis;Hiperkalsemi; Paget hastal\u0131\u011f\u0131; Refleks sempatik distrofi (algodistrofi veya Sudeck hastal\u0131\u011f\u0131)<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00dcr\u00fcn Ad\u0131: Kalsitonin somonu
\nCAS: 47931-85-1
\nMF: C145H240N44O48S2
\nMW: 3431.85
\nEINECS: 256-342-8
\nMol Dosya: 47931-85-1.mol<\/p>\n","protected":false},"featured_media":2114,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[],"product_tag":[1323],"class_list":{"0":"post-8361","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_tag-puya-supply-calcitonin-salmon-cas-47931-85-1-for-osteoporosis-tr","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product\/8361","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/comments?post=8361"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/media\/2114"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/media?parent=8361"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_brand?post=8361"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_cat?post=8361"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_tag?post=8361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}