{"id":8934,"date":"2021-12-17T03:38:43","date_gmt":"2021-12-17T08:38:43","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/sicak-satis-plecanatide-cas-467426-54-6-kronik-idiyopatik-kabizligi-tedavi-etmek-icin-kullanin-cic\/"},"modified":"2022-08-29T04:30:08","modified_gmt":"2022-08-29T08:30:08","slug":"sicak-satis-plecanatide-cas-467426-54-6-kronik-idiyopatik-kabizligi-tedavi-etmek-icin-kullanin-cic","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/tr\/product\/sicak-satis-plecanatide-cas-467426-54-6-kronik-idiyopatik-kabizligi-tedavi-etmek-icin-kullanin-cic\/","title":{"rendered":"S\u0131cak Sat\u0131\u015f Plecanatide CAS 467426-54-6 Kronik idiyopatik kab\u0131zl\u0131\u011f\u0131 tedavi etmek i\u00e7in kullan\u0131n (CIC)"},"content":{"rendered":"

S\u0131cak Sat\u0131\u015f Plecanatide CAS 467426-54-6 Kronik idiyopatik kab\u0131zl\u0131\u011f\u0131 tedavi etmek i\u00e7in kullan\u0131n (CIC)<\/strong><\/h2>\n

\u00dcr\u00fcn Ad\u0131: Plecanatide
\nE\u015f Anlaml\u0131lar\u0131: Plecanatide;ASN-ASP-GLU-CYS-GLU-LEU-CYS-VAL-ASN-VAL-ALA-CYS-THR-GLY-CYS-LEU(DISULFIDE BAND CYS1&CYS3, CYS2&CYS4);Plecanatide Impurtiy;L-Leucine, L-asparaginyl-L-\u03b1-aspartil-L-\u03b1-glutamil-L-cysteinyl-L-\u03b1-glutamil-L-leucyl-L-cysteinyl-L-valyl-L- asparaginil-L-valil-L-alanil-L-sisteinil-L-threonilglisil-L-sisteinil-, siklik (4\u219212),(7\u219215)-bis(dis\u00fclfid);Plekanatid fandakemi;Plekanatid safs\u0131zl\u0131\u011f\u0131;Plekanatid USP\/ EP\/BP;Prikanatid
\nCAS: 467426-54-6
\nMF: C65H104N18O26S4
\nMW: 1681.89
\nMol Dosya: 467426-54-6.mol<\/p>\n

Plecanatide yeni bir guanilat siklaz enzimini etkileyen, ba\u011f\u0131rsak s\u0131v\u0131s\u0131 salg\u0131lanmas\u0131n\u0131 uyaran ve ba\u011f\u0131rsak hareketlerini h\u0131zland\u0131ran ila\u00e7. 16 amino asitten olu\u015fan oral peptid, bir insan gastrointestinal peptidi olan \u00fcriner guanozini taklit edecek \u015fekilde tasarlanm\u0131\u015ft\u0131r. \u0130lk olarak Amerika Birle\u015fik Devletleri'nde Callisto Pharmaceuticals taraf\u0131ndan geli\u015ftirilen ve geli\u015ftirme i\u00e7in Synergy Pharmaceuticals'a aktar\u0131lan prokainatid, yeti\u015fkinlerde CIC tedavisi i\u00e7in 19 Ocak Chemicalbook 2017'de ABD G\u0131da ve \u0130la\u00e7 Dairesi (FDA) taraf\u0131ndan pazarlama i\u00e7in onayland\u0131.Prokainatid, \u00fcroguanozinin bir analo\u011fudur. (uroguanilin) ve 16 amino asit i\u00e7eren siklik bir peptit olan uroguanilin'in bir analo\u011fudur ve idrarda sodyum at\u0131l\u0131m\u0131n\u0131 destekleyen, gastrointestinal sistemdeki asit-baz iyonlar\u0131n\u0131 d\u00fczenleyen, s\u0131v\u0131y\u0131 ind\u00fckleyen bir guanilat siklaz resept\u00f6r agonisti i\u015flevine sahiptir. gastrointestinal sisteme ta\u015f\u0131n\u0131r ve gastrointestinal sistemin peristaltizmini artt\u0131r\u0131r.<\/p>\n

www.DeepL.com\/Translator (\u00fccretsiz s\u00fcr\u00fcm) ile \u00e7evrilmi\u015ftir<\/p>\n

Plecanatide'in \u0130\u015flevi ve Uygulamas\u0131<\/strong>
\nProcainide bir guanilatsiklaz-C (GC-C) resept\u00f6r agonisti, idrarla sodyum at\u0131l\u0131m\u0131n\u0131 artt\u0131r\u0131r, gastrointestinal kanaldaki asit-baz iyonlar\u0131n\u0131 d\u00fczenler, mideye s\u0131v\u0131 ta\u015f\u0131nmas\u0131n\u0131 ind\u00fckler. e gastrointestinal sistem ve gastrointestinal sistemdeki peristaltizmi artt\u0131r\u0131r ve yeti\u015fkinlerde CIC tedavisi i\u00e7in endikedir.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00dcr\u00fcn Ad\u0131: Plecanatide
\nCAS: 467426-54-6
\nMF: C65H104N18O26S4
\nMW: 1681.89
\nMol Dosya: 467426-54-6.mol<\/strong><\/p>\n","protected":false},"featured_media":2177,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[460],"product_tag":[812],"class_list":{"0":"post-8934","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-gastrointestinal-sistem-peptidi","7":"product_tag-plecanatide-cas-467426-54-6-use-for-treat-chronic-idiopathic-constipation-tr","8":"desktop-align-left","9":"tablet-align-left","10":"mobile-align-left","12":"first","13":"instock","14":"shipping-taxable","15":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product\/8934","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/comments?post=8934"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/media\/2177"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/media?parent=8934"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_brand?post=8934"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_cat?post=8934"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_tag?post=8934"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}