{"id":8958,"date":"2021-12-17T03:40:01","date_gmt":"2021-12-17T08:40:01","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/linaclotide-cas-851199-59-2-kabizlikli-irritabl-bagirsak-sendromunu-ibs-c-ve-kronik-idiyopatik-kabizligi-cic-tedavi-etmek-icin\/"},"modified":"2021-12-17T03:40:01","modified_gmt":"2021-12-17T08:40:01","slug":"linaclotide-cas-851199-59-2-kabizlikli-irritabl-bagirsak-sendromunu-ibs-c-ve-kronik-idiyopatik-kabizligi-cic-tedavi-etmek-icin","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/tr\/product\/linaclotide-cas-851199-59-2-kabizlikli-irritabl-bagirsak-sendromunu-ibs-c-ve-kronik-idiyopatik-kabizligi-cic-tedavi-etmek-icin\/","title":{"rendered":"Linaclotide CAS 851199-59-2 Kab\u0131zl\u0131kl\u0131 irritabl ba\u011f\u0131rsak sendromunu (IBS-C) ve kronik idiyopatik kab\u0131zl\u0131\u011f\u0131 (CIC) tedavi etmek i\u00e7in"},"content":{"rendered":"

Linaclotide CAS 851199-59-2 Kab\u0131zl\u0131kl\u0131 irritabl ba\u011f\u0131rsak sendromunu (IBS-C) ve kronik idiyopatik kab\u0131zl\u0131\u011f\u0131 (CIC) tedavi etmek i\u00e7in<\/strong><\/h2>\n

\u00dcr\u00fcn Ad\u0131: Linaclotide
\nE\u015f anlaml\u0131lar: Linacllotide;Linaclotide;Linaelotide Acetate;Linaelotide;CY-14;Liclotide;Argpessin;L-Tirozin, L-sisteinil-L-sisteinil-L-\u03b1-glutamil-L-tirosil -L-sisteinil-L-sisteinil-L-asparaginil-L-prolil-L-alanil-L-sisteinil-L-treonilglisil-L-sisteinil-, siklik (1\u21926),(2\u219210),(5\u2192 13)-tris(dis\u00fclfid)
\nCAS: 851199-59-2
\nMF: C59H79N15O21S6
\nMW: 1526.74
\nEINECS:
\n\u00dcr\u00fcn Kategorileri: \u0130nhibit\u00f6rler
\nMol Dosyas\u0131: 851199-59 -2.mol<\/p>\n

Linaclotide Spesifikasyonu<\/strong> <\/p>\n\n\n\n\n\n\n\n\n\n\n\n
Test i\u00e7eri\u011fi<\/td>\n \u00d6zellikler<\/td>\n<\/tr>\n
G\u00f6r\u00fcn\u00fcm<\/td>\n Beyaz veya neredeyse beyaz kristal toz<\/td>\n<\/tr>\n
HPLC ile kimlik<\/td>\n Reaksiyon referans madde ile ayn\u0131d\u0131r<\/td>\n<\/tr>\n
Amino Asit Bile\u015fimi<\/td>\n \u00b1%20 teorik<\/td>\n<\/tr>\n
Safl\u0131k (HPLC)<\/td>\n \u2265 %98,0<\/td>\n<\/tr>\n
\u0130lgili Madde(HPLC ile)<\/td>\n Toplam Kirlilik(%)\u2264 %2,0
\nEn B\u00fcy\u00fck Tek Kirlilik(%)\u2264 %1,0<\/td>\n<\/tr>\n
Asetat \u0130\u00e7eri\u011fi (HPLC ile)<\/td>\n \u226415%<\/td>\n<\/tr>\n
Su \u0130\u00e7eri\u011fi (HPLC'ye g\u00f6re)<\/td>\n \u22645.0%<\/td>\n<\/tr>\n
Bakteriyel Endotoksinler<\/td>\n \u22645IU\/mg<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Linaclotid'in \u0130\u015flevi ve Uygulamas\u0131<\/strong>
\nLinaclotide, guanilat siklaz 2C'nin bir peptit agonistidir.<\/p>\n

Bu bile\u015fik, kolonik duyu n\u00f6ronlar\u0131n\u0131n aktivasyonunu azalt\u0131r, a\u011fr\u0131y\u0131 azalt\u0131r; ve d\u00fcz kas kas\u0131lmas\u0131n\u0131 art\u0131ran ve b\u00f6ylece ba\u011f\u0131rsak hareketlerini destekleyen kolonik motor n\u00f6ronlar\u0131 aktive eder.<\/p>\n

Kronik idiyopatik kab\u0131zl\u0131k ve kab\u0131zl\u0131\u011f\u0131n bask\u0131n oldu\u011fu irritabl ba\u011f\u0131rsak sendromunun (IBS-C) tedavisi i\u00e7in A\u011fustos 2012'de FDA taraf\u0131ndan onaylanm\u0131\u015ft\u0131r. ) yeti\u015fkinlerde.<\/p>\n","protected":false},"excerpt":{"rendered":"

\u00dcr\u00fcn Ad\u0131: Linaclotide
\nCAS: 851199-59-2
\nMF: C59H79N15O21S6
\nMW: 1526.74
\nEINECS:
\n\u00dcr\u00fcn Kategorileri: \u0130nhibit\u00f6rler
\nMol Dosyas\u0131: 851199-59-2. mol<\/p>\n","protected":false},"featured_media":2135,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[460],"product_tag":[],"class_list":{"0":"post-8958","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-gastrointestinal-sistem-peptidi","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product\/8958","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/comments?post=8958"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/media\/2135"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/media?parent=8958"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_brand?post=8958"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_cat?post=8958"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/tr\/wp-json\/wp\/v2\/product_tag?post=8958"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}