{"id":7417,"date":"2021-12-16T07:58:33","date_gmt":"2021-12-16T12:58:33","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-de-tang-huyet-ap\/"},"modified":"2021-12-16T07:58:33","modified_gmt":"2021-12-16T12:58:33","slug":"angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-de-tang-huyet-ap","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/vi\/product\/angiotensin-ii-angiotensin-ii-human-cas-4474-91-3-de-tang-huyet-ap\/","title":{"rendered":"Angiotensin II \/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 \u0110\u1ec3 t\u0103ng huy\u1ebft \u00e1p"},"content":{"rendered":"<h2><strong>Angiotensin II \/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 \u0110\u1ec3 t\u0103ng huy\u1ebft \u00e1p<\/strong><\/h2>\n<p> T\u00ean s\u1ea3n ph\u1ea9m: ANGIOTENSIN II, HUMAN<br \/>\n Tr\u00ecnh t\u1ef1: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH<br \/>\n T\u1eeb \u0111\u1ed3ng ngh\u0129a: DRVYIHPF; [ILE5] -ANGIOTENSIN 2; HYPERTENSION II CON NG\u01af\u1edcI; L-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE; H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH; FLUORESCEIN-NHCS-NH-ASP-ARG- VAL-TYR-ILE-HIS-PRO-PHE-OH; ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH 2CH3CHOOH H2O; ANGIOTENSIN II, CON NG\u01af\u1edcI<br \/>\n CAS: 4474-91-3 &lt;&amp; &gt; MF: C50H71N13O12<br \/>\n MW: 1046.2<br \/>\n EINECS: 2017-001-1<br \/>\n Danh m\u1ee5c s\u1ea3n ph\u1ea9m: Angiotensin; peptide<br \/>\n Mol T\u1ec7p: 4474-91-3.mol <\/p>\n<p> \u0110\u00f3 l\u00e0 \u0111\u01b0\u1ee3c bi\u1ebft r\u1eb1ng c\u00e1c m\u00f4 kh\u1ed1i u bao g\u1ed3m c\u00e1c h\u1ea1ch b\u1ea1ch huy\u1ebft di c\u0103n \u0111\u01b0\u1ee3c c\u1ea5u t\u1ea1o b\u1edfi c\u00e1c m\u1ea1ch m\u1edbi ph\u00e1t tri\u1ec3n thi\u1ebfu kh\u1ea3 n\u0103ng t\u1ef1 \u0111i\u1ec1u h\u00f2a l\u01b0u l\u01b0\u1ee3ng m\u00e1u v\u00e0 ch\u1ec9 b\u1ecb \u1ea3nh h\u01b0\u1edfng th\u1ee9 hai b\u1edfi c\u00e1c m\u1ea1ch soma \u0111\u00e1p \u1ee9ng. Angiotensin II \u1edf ng\u01b0\u1eddi (AT II). m\u1ed9t lo\u1ea1i thu\u1ed1c v\u1eadn m\u1ea1ch, \u0111\u00e3 \u0111\u01b0\u1ee3c gi\u1edbi thi\u1ec7u \u1edf Nh\u1eadt B\u1ea3n \u0111\u1ec3 c\u1ea3i thi\u1ec7n hi\u1ec7u qu\u1ea3 c\u1ee7a h\u00f3a tr\u1ecb li\u1ec7u to\u00e0n th\u00e2n. \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c b\u1ec7nh ung th\u01b0 ti\u1ebfn tri\u1ec3n kh\u00e1c nhau, ti\u00eam truy\u1ec1n IV AT II \u0111\u1ec3 \u0111\u1ea1t \u0111\u01b0\u1ee3c huy\u1ebft \u00e1p trung b\u00ecnh b\u1eb1ng 1,5 l\u1ea7n so v\u1edbi ban \u0111\u1ea7u (nh\u01b0ng kh\u00f4ng qu\u00e1 150 mm Hg), sau \u0111\u00f3 ti\u00eam m\u1ed9t li\u1ec1u thu\u1ed1c \u0111\u1ed9c t\u1ebf b\u00e0o th\u00f4ng th\u01b0\u1eddng l\u00e0m t\u0103ng l\u01b0u l\u01b0\u1ee3ng m\u00e1u g\u1ea5p 5-7 l\u1ea7n trong c\u00e1c m\u00f4 kh\u1ed1i u v\u00e0 do \u0111\u00f3, l\u00e0m t\u0103ng ph\u00e2n ph\u1ed1i thu\u1ed1c \u0111\u1ebfn m\u00f4 \u0111\u00edch, d\u1eabn \u0111\u1ebfn t\u0103ng c\u01b0\u1eddng t\u00e1c d\u1ee5ng h\u00f3a tr\u1ecb li\u1ec7u. Ch\u1ebf \u0111\u1ed9 h\u00f3a tr\u1ecb li\u1ec7u g\u00e2y t\u0103ng huy\u1ebft \u00e1p n\u00e0y c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n m\u1ed9t c\u00e1ch an to\u00e0n v\u1edbi \u00edt t\u00e1c d\u1ee5ng ph\u1ee5 nh\u1ea5t. <\/p>\n<p> <strong>Angiotensin II \/ ANGIOTENSIN II, HUMAN CAS 4474-91-3 T\u00ednh ch\u1ea5t h\u00f3a h\u1ecdc<\/strong><br \/>\n \u0110i\u1ec3m s\u00f4i 809,08 \u00b0 C (\u01b0\u1edbc t\u00ednh s\u01a1 b\u1ed9) &lt;&amp; &gt; m\u1eadt \u0111\u1ed9 1.1257 (\u01b0\u1edbc t\u00ednh s\u01a1 b\u1ed9)<br \/>\n ch\u1ec9 s\u1ed1 kh\u00fac x\u1ea1 1.6700 (\u01b0\u1edbc t\u00ednh)<br \/>\n RTECS BW2165000<br \/>\n nhi\u1ec7t \u0111\u1ed9 l\u01b0u tr\u1eef. \u0110\u1ec3 n\u01a1i t\u1ed1i, kh\u00f4ng kh\u00ed tr\u01a1, B\u1ea3o qu\u1ea3n trong t\u1ee7 \u0111\u00f4ng, d\u01b0\u1edbi -20 \u00b0 C<br \/>\n D\u1ea1ng b\u1ed9t<br \/>\n pka pK1: 10,37 (25 \u00b0 C)<br \/>\n m\u00e0u cam<br \/>\n T\u00ednh tan trong n\u01b0\u1edbc H\u00f2a tan trong n\u01b0\u1edbc (25 mg \/ ml), v\u00e0 5% Axit axetic (1 mg \/ ml).<br \/>\n InChIKey CZGUSIXMZVURDU-JZXHSEFVSA-N<br \/>\n CAS DataBase Reference 4474-91-3 <\/p>\n<p> <strong>Ch\u1ee9c n\u0103ng v\u00e0 \u1ee9ng d\u1ee5ng c\u1ee7a Angiotensin II \/ ANGIOTENSIN II, CON NG\u01af\u1edcI CAS 4474-91-3<\/strong><br \/>\n Angiotensin II l\u00e0 m\u1ed9t peptit ng\u1eafn bao g\u1ed3m 8 axit amin, v\u00e0 ch\u1ee9c n\u0103ng sinh l\u00fd c\u1ee7a n\u00f3 ch\u1ee7 y\u1ebfu l\u00e0 t\u0103ng huy\u1ebft \u00e1p b\u1eb1ng c\u00e1ch co th\u1eaft c\u00e1c \u0111\u1ed9ng m\u1ea1ch nh\u1ecf kh\u1eafp c\u01a1 th\u1ec3. Ngo\u00e0i ra, n\u00f3 c\u0169ng c\u00f3 th\u1ec3 th\u00fac \u0111\u1ea9y s\u1ef1 b\u00e0i ti\u1ebft aldosterone c\u1ee7a v\u1ecf th\u01b0\u1ee3ng th\u1eadn, ho\u1ea1t \u0111\u1ed9ng tr\u00ean \u1ed1ng th\u1eadn \u0111\u1ec3 b\u1ea3o qu\u1ea3n natri, n\u01b0\u1edbc v\u00e0 kali, do \u0111\u00f3 l\u00e0m t\u0103ng th\u1ec3 t\u00edch m\u00e1u v\u00e0 huy\u1ebft \u00e1p. <\/p>\n<p> <strong>C\u00f4ng d\u1ee5ng c\u1ee7a Angiotensin II \/ ANGIOTENSIN II, CON NG\u01af\u1edcI CAS 4474-91-3<\/strong><br \/>\n 1. H\u1ed3i sinh tim ph\u1ed5i &#8211; ch\u01b0a ph\u1ea3i l\u00e0 \u1ee9ng d\u1ee5ng \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn<br \/>\n 2. M\u1ed9t peptit li\u00ean quan \u0111\u1ebfn vi\u1ec7c \u0111i\u1ec1u ch\u1ec9nh huy\u1ebft \u00e1p<br \/>\n 3. Angiotensin II l\u00e0 m\u1ed9t hormone peptide \u0111\u01b0\u1ee3c bi\u1ebft \u0111\u1ebfn nhi\u1ec1u nh\u1ea5t nh\u01b0 m\u1ed9t ch\u1ea5t co m\u1ea1ch v\u1edbi vai tr\u00f2 trung t\u00e2m trong t\u0103ng huy\u1ebft \u00e1p m\u00e3n t\u00ednh, suy tim v\u00e0 \u0111\u1ed9t qu\u1ef5. N\u00f3 l\u00e0 m\u1ed9t octapeptit th\u01b0\u1eddng \u0111\u01b0\u1ee3c t\u1ea1o ra b\u1eb1ng c\u00e1ch lo\u1ea1i b\u1ecf hai g\u1ed1c kh\u1ecfi angiotensin I b\u1edfi enzym chuy\u1ec3n \u0111\u1ed5i angiotensin (ACE). Angiotensin II l\u00e0 ph\u1ed1i t\u1eed c\u1ee7a \u00edt nh\u1ea5t hai th\u1ee5 th\u1ec3 ri\u00eang bi\u1ec7t, AT1 v\u00e0 AT2, m\u1ed7i th\u1ee5 th\u1ec3 g\u1ee3i l\u00ean c\u00e1c con \u0111\u01b0\u1eddng t\u00edn hi\u1ec7u v\u00e0 ph\u1ea3n \u1ee9ng sinh l\u00fd ri\u00eang bi\u1ec7t. S\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a c\u00e1c ch\u1ea5t \u0111\u1ed1i kh\u00e1ng \u0111\u1ed1i v\u1edbi c\u00e1c ph\u00e2n nh\u00f3m th\u1ee5 th\u1ec3 angiotensin II c\u1ee5 th\u1ec3 l\u00e0 m\u1ed9t gi\u1ea3i ph\u00e1p thay th\u1ebf c\u00f3 gi\u00e1 tr\u1ecb cho c\u00e1c ch\u1ea5t \u1ee9c ch\u1ebf ACE.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>T\u00ean s\u1ea3n ph\u1ea9m: ANGIOTENSIN II, HUMAN<br \/>\n CAS: 4474-91-3<br \/>\n MF: C50H71N13O12<br \/>\n MW: 1046.2<br \/>\n EINECS: 2017-001-1<br \/>\n Mol T\u1ec7p: 4474-91-3 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