{"id":8390,"date":"2021-12-16T13:26:58","date_gmt":"2021-12-16T18:26:58","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/pramlintide-acetate-cas-196078-30-5-la-mot-chat-chong-dai-thao-duong-cung-co-the-duoc-su-dung-trong-nghien-cuu-ung-thu-ruot\/"},"modified":"2021-12-16T13:26:58","modified_gmt":"2021-12-16T18:26:58","slug":"pramlintide-acetate-cas-196078-30-5-la-mot-chat-chong-dai-thao-duong-cung-co-the-duoc-su-dung-trong-nghien-cuu-ung-thu-ruot","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/vi\/product\/pramlintide-acetate-cas-196078-30-5-la-mot-chat-chong-dai-thao-duong-cung-co-the-duoc-su-dung-trong-nghien-cuu-ung-thu-ruot\/","title":{"rendered":"Pramlintide Acetate CAS 196078-30-5 l\u00e0 m\u1ed9t ch\u1ea5t ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong nghi\u00ean c\u1ee9u ung th\u01b0 ru\u1ed9t"},"content":{"rendered":"

Pramlintide Acetate CAS 196078-30-5 l\u00e0 m\u1ed9t ch\u1ea5t ch\u1ed1ng \u0111\u00e1i th\u00e1o \u0111\u01b0\u1eddng c\u0169ng c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng trong nghi\u00ean c\u1ee9u ung th\u01b0 ru\u1ed9t<\/strong><\/h2>\n

T\u00ean s\u1ea3n ph\u1ea9m: Pramlintide acetate
\n T\u1eeb \u0111\u1ed3ng ngh\u0129a: AMYLIN (HUMAN), 25-L-PROLINE-28-L-PROLINE-29-L-PROLINE-, ACETATE (MU\u1ed0I), HYDRATE; pramlintide acetate; pramlintide acetate hydrate ; 25-L-Proline-28-L-proline-29-L-proline-aMylin (huMan) Acetate Hydrate; AC-137 Acetate Hydrate, SyMlin Acetate Hydrate; Tripo-aMylin Acetate Hydrate; Pramlintide Acetate, Amylin Rat; Pramlintide acetate fandachem
\n CAS: 196078-30-5
\n MF: C173H273N51O56S2
\n MW: 4027.46
\n EINECS:
\n Danh m\u1ee5c s\u1ea3n ph\u1ea9m: Axit amin & d\u1eabn xu\u1ea5t; C\u01a1 s\u1edf & Thu\u1ed1c th\u1eed li\u00ean quan; Thu\u1ed1c t\u01b0\u01a1ng t\u1ef1; D\u1ecb v\u00f2ng; Ch\u1ea5t trung gian & H\u00f3a ch\u1ea5t t\u1ed1t; Nucleotides; Peptide; D\u01b0\u1ee3c ph\u1ea9m
\n Mol File: 196078-30-5.mol <\/p>\n

Pramlintide acetate l\u00e0 m\u1ed9t ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 amylin ti\u00eam cho ng\u01b0\u1eddi \u0111\u00e3 \u0111\u01b0\u1ee3c \u0111\u01b0a ra \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb c\u1ea3 lo\u1ea1i 1 v\u00e0 lo\u1ea1i 2 b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng, k\u1ebft h\u1ee3p v\u1edbi insulin. M\u1eb7c d\u00f9 n\u00f3 c\u0169ng l\u00e0 m\u1ed9t peptit 37 axit amin, nh\u01b0ng n\u00f3 kh\u00e1c v\u1edbi ti\u1ec1n th\u00e2n c\u1ee7a n\u00f3 b\u1edfi s\u1ef1 thay th\u1ebf Ala-25, Ser-28 v\u00e0 Ser-29 b\u1eb1ng c\u00e1c proline. Nh\u1eefng s\u1eeda \u0111\u1ed5i n\u00e0y kh\u00f4ng ch\u1ec9 c\u1ea3i thi\u1ec7n kh\u1ea3 n\u0103ng h\u00f2a tan c\u1ee7a peptit m\u00e0 c\u00f2n lo\u1ea1i b\u1ecf s\u1ef1 k\u1ebft t\u1ee5 \u0111\u01b0\u1ee3c quan s\u00e1t th\u1ea5y v\u1edbi amylin, d\u1eabn \u0111\u1ebfn m\u1ed9t ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 t\u1ed5ng h\u1ee3p \u1ed5n \u0111\u1ecbnh v\u1edbi vi\u1ec7c duy tr\u00ec ho\u1ea1t t\u00ednh sinh h\u1ecdc th\u00edch h\u1ee3p cho vi\u1ec7c s\u1eed d\u1ee5ng d\u01b0\u1ee3c ph\u1ea9m. Nh\u01b0 m\u1ed9t d\u1ea5u hi\u1ec7u v\u1ec1 hi\u1ec7u l\u1ef1c, Pramlintide acetate \u1ee9c ch\u1ebf s\u1ef1 g\u1eafn k\u1ebft amylin c\u1ee7a chu\u1ed9t \u0111\u00e3 \u0111\u01b0\u1ee3c kh\u1eed ph\u00f3ng x\u1ea1 v\u1edbi m\u00e0ng t\u00edch l\u0169y nh\u00e2n c\u1ee7a chu\u1ed9t v\u1edbi gi\u00e1 tr\u1ecb Ki l\u00e0 23 pM. C\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng c\u1ee7a n\u00f3 b\u1eaft ch\u01b0\u1edbc amylin; nh\u01b0 m\u1ed9t ch\u1ea5t k\u00edch th\u00edch th\u1ea7n kinh \u0111\u01b0\u1ee3c t\u1ea1o ra v\u1edbi insulin t\u1eeb t\u1ebf b\u00e0o \u03b2 tuy\u1ebfn t\u1ee5y \u0111\u1ec3 \u0111\u00e1p \u1ee9ng v\u1edbi b\u1eefa \u0103n, n\u00f3 tham gia v\u00e0o qu\u00e1 tr\u00ecnh c\u00e2n b\u1eb1ng n\u1ed9i m\u00f4i glucose. C\u1ea3 hai peptit \u0111\u1ec1u l\u00e0m gi\u1ea3m m\u1ee9c \u0111\u01b0\u1eddng huy\u1ebft sau \u0103n b\u1eb1ng c\u00e1ch \u1ee9c ch\u1ebf glucagon v\u00e0 b\u1eb1ng c\u00e1ch h\u1ea1n ch\u1ebf t\u1ed1c \u0111\u1ed9 l\u00e0m r\u1ed7ng d\u1ea1 d\u00e0y qua trung gian ph\u1ebf v\u1ecb, do \u0111\u00f3, l\u00e0m ch\u1eadm s\u1ef1 h\u1ea5p thu carbohydrate \u1edf ru\u1ed9t. H\u01a1n n\u1eefa, amylin, ho\u1eb7cPramlintide acetate, c\u00f3 th\u00eam l\u1ee3i \u00edch l\u00e0 g\u00e2y c\u1ea3m gi\u00e1c no sau \u0103n, d\u1eabn \u0111\u1ebfn gi\u1ea3m c\u00e2n \u1edf b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng lo\u1ea1i 2. V\u00ec Pramlintide acetate l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh l\u00e0m r\u1ed7ng d\u1ea1 d\u00e0y, n\u00ean n\u00f3 \u0111\u01b0\u1ee3c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n b\u1ecb li\u1ec7t d\u1ea1 d\u00e0y v\u00e0 nh\u1eefng b\u1ec7nh nh\u00e2n \u0111ang d\u00f9ng thu\u1ed1c l\u00e0m thay \u0111\u1ed5i nhu \u0111\u1ed9ng \u0111\u01b0\u1eddng ti\u00eau h\u00f3a (thu\u1ed1c kh\u00e1ng cholinergic, ch\u1eb3ng h\u1ea1n nh\u01b0 atropine) ho\u1eb7c l\u00e0m ch\u1eadm qu\u00e1 tr\u00ecnh h\u1ea5p thu ch\u1ea5t dinh d\u01b0\u1ee1ng \u1edf ru\u1ed9t (nh\u01b0 ch\u1ea5t \u1ee9c ch\u1ebf \u03b1-glucosidase). Pramlintide acetate c\u0169ng \u0111\u01b0\u1ee3c ch\u1ed1ng ch\u1ec9 \u0111\u1ecbnh \u1edf nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 khuynh h\u01b0\u1edbng h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft; do d\u00f9ng \u0111\u1ed3ng th\u1eddi v\u1edbi insulin, nguy c\u01a1 h\u1ea1 \u0111\u01b0\u1eddng huy\u1ebft do insulin tr\u1ea7m tr\u1ecdng. C\u00e1c t\u00e1c d\u1ee5ng ngo\u1ea1i \u00fd th\u01b0\u1eddng \u0111\u01b0\u1ee3c b\u00e1o c\u00e1o bao g\u1ed3m bu\u1ed3n n\u00f4n, n\u00f4n, ch\u00e1n \u0103n, nh\u1ee9c \u0111\u1ea7u, \u0111au b\u1ee5ng, m\u1ec7t m\u1ecfi, ch\u00f3ng m\u1eb7t, ho v\u00e0 vi\u00eam h\u1ecdng. <\/p>\n

Ch\u1ee9c n\u0103ng v\u00e0 \u1ee9ng d\u1ee5ng c\u1ee7a CAS 196078-30-5<\/strong> <\/p>\n

Pramlintide acetate l\u00e0 m\u1ed9t ch\u1ea5t t\u01b0\u01a1ng t\u1ef1 t\u1ed5ng h\u1ee3p c\u1ee7a polypeptide amyloid tuy\u1ebfn t\u1ee5y (Amylin, amylopectin) v\u00e0 l\u00e0 lo\u1ea1i thu\u1ed1c th\u1ee9 hai \u0111\u01b0\u1ee3c ch\u1ea5p thu\u1eadn \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng lo\u1ea1i 1 sau insulin. Trong th\u1ef1c h\u00e0nh l\u00e2m s\u00e0ng, pramlintide \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t lo\u1ea1i thu\u1ed1c b\u1ed5 tr\u1ee3 \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb b\u1ec7nh ti\u1ec3u \u0111\u01b0\u1eddng lo\u1ea1i 1 v\u00e0 lo\u1ea1i 2, ch\u1ee7 y\u1ebfu cho nh\u1eefng b\u1ec7nh nh\u00e2n ti\u1ec3u \u0111\u01b0\u1eddng kh\u00f4ng \u0111\u1ea1t \u0111\u01b0\u1ee3c k\u1ebft qu\u1ea3 mong \u0111\u1ee3i khi ch\u1ec9 d\u00f9ng insulin v\u00e0 k\u1ebft h\u1ee3p insulin v\u1edbi sulfonylureas v\u00e0 metformin. Pramlintide c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng k\u1ebft h\u1ee3p v\u1edbi insulin, nh\u01b0ng n\u00f3 kh\u00f4ng th\u1ec3 thay th\u1ebf insulin.<\/p>\n","protected":false},"excerpt":{"rendered":"

T\u00ean s\u1ea3n ph\u1ea9m: Pramlintide axetat
\n CAS: 196078-30-5
\n MF: C173H273N51O56S2
\n MW: 4027.46
\n Mol T\u1ec7p: 196078-30-5.mol<\/p>\n","protected":false},"featured_media":2220,"comment_status":"open","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"site-sidebar-layout":"default","site-content-layout":"default","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[352,352,352],"product_tag":[1300],"class_list":{"0":"post-8390","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-peptide-tieu-duong","9":"product_tag-pramlintide-acetate-cas-196078-30-5-is-an-antidiabetic-agent-that-can-also-be-used-in-bowel-cancer-research-vi","10":"desktop-align-left","11":"tablet-align-left","12":"mobile-align-left","14":"first","15":"instock","16":"shipping-taxable","17":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/product\/8390","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/comments?post=8390"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/media\/2220"}],"wp:attachment":[{"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/media?parent=8390"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/product_brand?post=8390"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/product_cat?post=8390"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/puyapeptide.net\/vi\/wp-json\/wp\/v2\/product_tag?post=8390"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}