{"id":7255,"date":"2021-12-16T07:18:56","date_gmt":"2021-12-16T12:18:56","guid":{"rendered":"https:\/\/puyapeptide.net\/product\/enfuvirtide-enfuvirtide-acetate-cas-159519-65-0-%e7%94%a8%e4%ba%8e%e6%8a%97-hiv\/"},"modified":"2021-12-16T07:18:56","modified_gmt":"2021-12-16T12:18:56","slug":"enfuvirtide-enfuvirtide-acetate-cas-159519-65-0-%e7%94%a8%e4%ba%8e%e6%8a%97-hiv","status":"publish","type":"product","link":"https:\/\/puyapeptide.net\/zh-hans\/product\/enfuvirtide-enfuvirtide-acetate-cas-159519-65-0-%e7%94%a8%e4%ba%8e%e6%8a%97-hiv\/","title":{"rendered":"Enfuvirtide\/Enfuvirtide Acetate CAS 159519-65-0 \u7528\u4e8e\u6297 HIV"},"content":{"rendered":"

Enfuvirtide\/Enfuvirtide Acetate CAS 159519-65-0 \u7528\u4e8e\u6297 HIV<\/strong><\/h2>\n

\u4ea7\u54c1\u540d\u79f0\uff1a\u6069\u592b\u97e6\u80bd
\n\u5e8f\u5217\uff1aAc-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys< &>-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2
\n\u540c\u4e49\u8bcd\uff1aEnfuvirtide\uff1b T-2;Enfuvirtide Acetate (T-20);ENFUVIRTIDE(T-20) 98+%;Enfurvitide(T-20);Pentafuside;Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile -Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn -Trp-Phe-NH{2};Enfuvirtide;Aids059486
\nCAS\uff1a159519-65-0
\nMF\uff1aC204H301N51O64
\nMW\uff1a4491.92
\nEINECS\uff1a641-385-0
\n\u4ea7\u54c1\u7c7b\u522b:proteins;Peptide
\nMol File:159519-65-0.mol<\/p>\n

\u662f\u4e00\u79cd\u5408\u6210\u7684HIV\u878d\u5408\u80bd\u6291\u5236\u5242\uff0c\u53ef\u4e0e\u75c5\u6bd2\u5305\u819c\u7cd6\u86cb\u767d\u7ed3\u5408\uff0c\u963b\u6b62\u75c5\u6bd2\u6240\u9700\u7684\u6784\u8c61\u53d8\u5316\u4e0e\u7ec6\u80de\u819c\u878d\u5408\uff0c\u4ece\u800c\u6291\u5236 HIV-1 \u7684\u590d\u5236\u3002Enfevir \u80bd\u6e90\u81ea gp41 \u7684 HR2 \u7ed3\u6784\u57df\u4e2d\u7684\u5929\u7136\u6c28\u57fa\u9178\u5e8f\u5217\u3002 Enfevir\u80bd\u901a\u8fc7\u6a21\u62dfHR2\u7ed3\u6784\u57df\u7684\u6d3b\u6027\u5e76\u4e0egp41\u7684HR1\u7ed3\u6784\u57df\u7ade\u4e89\u6027\u7ed3\u5408\uff0c\u963b\u6b62HR1\u548cHR2\u4e4b\u95f4\u7684\u76f8\u4e92\u4f5c\u7528\u4ee5\u53caGp41\u6784\u578b\u7684\u6539\u53d8\uff0c\u4ece\u800c\u963b\u6b62\u75c5\u6bd2\u4e0e\u5bbf\u4e3b\u7ec6\u80de\u7684\u878d\u5408\u3002<\/p>\n

Enfuvirtide \u662f\u4e00\u7c7b\u65b0\u7684 HIV \u7597\u6cd5\u4e2d\u7684\u7b2c\u4e00\u79cd\uff0c\u901a\u8fc7\u6291\u5236\u75c5\u6bd2\u548c\u7ec6\u80de\u819c\u7684\u878d\u5408\u6765\u5e72\u6270 HIV-1 \u7684\u8fdb\u5165\u3002\u5b83\u4e0e\u75c5\u6bd2\u5305\u819c\u7cd6\u86cb\u767d ghe gp41 \u4e9a\u57fa\u4e2d\u7684\u7b2c\u4e00\u4e2a\u4e03\u80bd\u91cd\u590d\u5e8f\u5217 (HR1) \u7ed3\u5408\uff0c\u9632\u6b62\u4e0e\u7ec6\u80de\u819c\u878d\u5408\u6240\u9700\u7684\u6784\u8c61\u53d8\u5316\uff0c\u56e0\u6b64\u4ee3\u8868\u4e86\u4e00\u79cd\u65b0\u673a\u5236\u3002\u5b83\u662f\u8fd9\u79cd\u7ed3\u5408\u7684\u6709\u6548\u6291\u5236\u5242\uff0c\u5728\u5b9e\u9a8c\u5ba4\u548c\u521d\u7ea7\u5206\u79bb\u682a\uff08HIV-1 \u8fdb\u5316\u679d A-G\uff09\u4e2d\u7684 IC50 \u4e3a 4 \u81f3 280 nM\uff0818-1260 ng\/mL\uff09\uff0c\u4f46\u5bf9 HIV-2 \u51e0\u4e4e\u6ca1\u6709\u6d3b\u6027\u3002\u7531\u4e8e\u5176\u72ec\u7279\u7684\u673a\u5236\uff0c\u5b83\u4e0d\u4f1a\u5bf9 NRTI\u3001NNRTI \u548c PI \u8868\u73b0\u51fa\u4ea4\u53c9\u8010\u836f\u6027\u3002\u5b83\u662f\u901a\u8fc7\u5316\u5b66\u5408\u6210\u5236\u5907\u7684\uff0c\u4f7f\u7528\u6eb6\u6db2\u548c\u56fa\u76f8\u6b65\u9aa4\u7684\u7ec4\u5408\u3002\u56fa\u76f8\u6b65\u9aa4\u5229\u7528 fmoc \u4fdd\u62a4\u548c\u9178\u654f\u611f\u7684 2-\u6c2f\u4e09\u82ef\u7532\u57fa\u6c2f\u6811\u8102\u6765\u751f\u4ea7\u957f\u5ea6\u4e3a 9 \u5230 16 \u4e2a\u6c28\u57fa\u9178\u7684\u80bd\u3002 <\/p>\n

Enfuvirtide\/Enfuvirtide Acetate CAS 159519-65-0 \u5316\u5b66\u6027\u8d28<\/strong>
\n\u50a8\u5b58\u6e29\u5ea6\u3002 -20\u00b0C
\n\u5f62\u6210\u7c89\u672b
\n\u989c\u8272\u767d\u8272\u81f3\u7070\u767d\u8272<\/p>\n

Enfuvirtide\/Enfuvirtide Acetate\u7684\u7528\u9014 CAS 159519-65-0<\/strong>
\n\u4e0e\u9006\u8f6c\u5f55\u9176\u836f\u7269\u8054\u5408\u7528\u4e8e\u4eba\u7c7b\u514d\u75ab\u7f3a\u9677\u75c5\u6bd2 (HIV) \u611f\u67d3\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u4ea7\u54c1\u540d\u79f0\uff1aEnfuvirtide
\nCAS\uff1a159519-65-0
\nMF\uff1aC204H301N51O64
\nMW\uff1a4491.92
\nEINECS\uff1a641-385-0
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